Acidifier and lysozyme may have a significant impact on growth performance and body defense in broilers. The experiment was conducted to evaluate the effects of dietary acidifier and lysozyme on physiognomies (live body weight and body weight gain), feed conversion ratio (FCR) and selected hemato-biochemical parameters in broiler chicken. A total of 60, day old Lohman broiler chicks were collected and reared up to 28 days with timely vaccination. At day 14, the chicks were randomly divided into four equal groups: A, B, C and D (n=15). Group A was considered as non-treated control; group B was supplemented with acidifier, group C with lysozyme and group D with both acidifier and lysozyme through drinking water. Results showed that acidifier, lysozyme and combined groups had significantly higher live body weight and lower feed conversion ratio, FCR (p<0.05) compared to the control group. Total erythrocyte count (TEC), hemoglobin concentration and packed cell volume (PCV) were significantly higher (p<0.05) especially in lysozyme supplemented group. Serum lipid profile (total cholesterol, triglyceride and LDL cholesterol) were significantly decreased in the acidifier supplemented group, whereas HDL cholesterol was increased (p<0.05). Lysozyme supplemented birds showed an increased level of total cholesterol and significant (p<0.05) decrease in triglyceride and LDL level. Combined supplementation showed almost similar results as lysozyme. Serum alanine transaminase (ALT), aspartate transaminase (AST) and creatinine concentration didn’t differ significantly upon supplementations. It is concluded that acidifier and lysozyme could be used in broiler feed for better growth performance and hemato-biochemical profile.

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Journal of Advanced Biotechnology and Experimental Therapeutics

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